Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
Atlantic herring Protein: Clu h 1 | β-Parvalbumin
Empirical Proteotypic Peptide Explorer:
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
Sequence - 109 amino acids
MALASLLKGADIDAALKACEAKDSFKHKDFFAKIGLATKSAADLKKAFEIIDQDKSGFIEEEELKLFLQNFKAGARALTDAETKAFLKAGDADGDGMIGVDEFAVMIKP
UniProt: C6GKU6 IUIS: Clu h 1Peptide Selector Tool
Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
Minimum length:
Maximum length:
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| ^ | MALASLLK | G | 0 | 0.197 | 0.4112 |
| K | GADIDAALK | A | 0 | 0.294 | 0.56118 |
| K | AFEIIDQDK | S | 0 | 0.34 | 0.5003 |
| K | SGFIEEEELK | L | 0 | 0.391 | 0.547 |
| K | LFLQNFK | A | 0 | 0.32 | 0.19254 |
| R | ALTDAETK | A | 0 | 0.23 | 0.4154 |
| K | AGDADGDGMIGVDEFAVMIKP | $ | 0 | 0.407 | 0.27328 |
| ^ | MAFAGLLSDADIAAALGACTAADTFDHK | S | 0 | 0.557 | 0.1522 |
| K | KPFYIIDQDK | S | 0 | 0.261 | 0.387 |
| K | SGFIEEEELK | L | 0 | 0.391 | 0.547 |
| K | LFLQNFK | A | 0 | 0.32 | 0.19254 |
| K | AFLAAGDADGDGMIGVDEFAVMVK | A | 0 | 0.462 | 0.15506 |
| ^ | MAFAAFLK | E | 0 | 0.295 | 0.38974 |
| K | EADITAALGACK | G | 0 | 0.565 | 0.785 |
| K | GADSFDHK | A | 0 | 0.254 | 0.14468 |
| K | AFEIIDQDK | S | 0 | 0.34 | 0.5003 |
| K | SGFIEEEELK | L | 0 | 0.391 | 0.547 |
| K | LFLQNFCK | G | 0 | 0.362 | 0.19102 |
| R | ALTDGETK | K | 0 | 0.21 | 0.2659 |
| K | AGDSDNDGK | I | 0 | 0.252 | 0.10896 |
| K | IGIDEFAALINH | $ | 0 | 0.536 | 0.2339 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.